Patent · US Active

De novo binding domain containing polypeptides and uses thereof

US10647775B2 · kind B2 · utility

9Cited by
5References
24Claims
0Family size

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Key dates

Filing dateApr 4, 2016
Grant dateMay 12, 2020
Priority date—
Expiry dateOct 10, 2036

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/70596
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are de novo binding domain containing polypeptides (DBDpp) that specifically bind a target of interest. Nucleic acids encoding the DBDpp, and vectors and host cells containing the nucleic acids are also provided. Libraries of DBDpp, methods of producing and screening such libraries and the DBDpp identified from such libraries and screens are also encompassed. Methods of making and using the DBDpp are additionally provided. Such uses include, without limitation, affinity purification, and diagnostic and therapeutic applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.