Online chemical derivatization using a cooled programmed temperature vaporization inlet

US10648955B2 · kind B2 · utility

Assignee

• The Government of the United States of America, as represented by the Secretary of the Navy · US

Inventors

• Lauryn E. DeGreeff · Washington, US
• Christopher J. Katilie · Washington, US

Key dates

• Filing date: Feb 23, 2018
• Grant date: May 12, 2020
• Expiry date: Oct 29, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/201
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A method of detecting an analyte by: providing a derivatizing agent that is reactive with the analyte; delivering the derivatizing agent into a chamber; delivering a sample of a gas suspected of containing the analyte into the chamber before or after delivering the derivatizing agent, while the chamber is maintained at a temperature that retains the derivatizing agent and any analyte and that allows reaction between the derivatizing agent and any analyte in the chamber to form a derivatized analyte; warming the chamber to cause evaporation of any derivatized analyte; and delivering the derivatized analyte in the chamber into a gas chromatograph column.