Non-invasive visualization and quantification of natural pigments
US10653355B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 5, 2016 |
| Grant date | May 19, 2020 |
| Priority date | — |
| Expiry date | Nov 2, 2036 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/655
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system for visualizing melanin present in tissue can include an imaging system to record a signal based on a presence of melanin in tissue and a display device to display an image based on the signal. A first laser source can emit a Stokes pulse train and a second laser source can emit a pump pulse train. Both the first laser source and the second laser source comprise a tunable center wavelength or frequency. An energy difference between a frequency of the Stokes pulse train and a frequency of the pump pulse train is from 1750 cm−1 to 2250 cm−1. The Stokes and the pump pulse train overlap in space and time. A scanning mechanism focuses the combined Stokes pulse train and pump pulse train within the tissue and scans across the tissue. A detector detects the signal based on a presence of melanin within the tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.