Substituted imidazoles as N-type calcium channel blockers

US10653673B2 · kind B2 · utility

Assignee

• Janssen Pharmaceuticals, Inc. · BE

Inventors

• Ishtiyaque Ahmad · Darsi, IN
• Rajagopal Bakthavatchalam · Branford, US
• Sivaramakrishna Battula · Bengaluru, IN
• Henricus Jacobus Maria Gijsen · Breda, NL
• Saravanan Vadivelu · Bengaluru, IN
• Mark Wall · Lansdale, US
• Christopher Flores · Lansdale, US

Key dates

• Filing date: Feb 9, 2018
• Grant date: May 19, 2020
• Expiry date: Feb 9, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, and G are defined herein.