Patent · US Active

High purity RNA compositions and methods for preparation thereof

US10653712B2 · kind B2 · utility

63Cited by
22References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 2018
Grant dateMay 19, 2020
Priority date
Expiry dateJun 6, 2038

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/6851
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to improved RNA compositions for use in therapeutic applications. The RNA compositions are particularly suited for use in human therapeutic application (e.g., in RNA therapeutics). The RNA compositions are made by improved processes, in particular, improved in vitro-transcription (IVT) processes. The invention also relates to methods for producing and purifying RNA (e.g, therapeutic RNAs), as well as methods for using the RNA compositions and therapeutic applications thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.