Patent · US Active

Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus

US10653766B2 · kind B2 · utility

0Cited by

3References

28Claims

0Family size

Assignee

Bavarian Nordic A/S · DK

Inventors

Cédric Cheminay · Munich, DE
Robin Steigerwald · Munich, DE
Ariane Volkmann · Andechs, DE

Key dates

Filing date	Mar 12, 2015
Grant date	May 19, 2020
Priority date	—
Expiry date	Apr 17, 2035

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to MVA can vastly increase the B cell response and particularly neutralizing antibodies against vaccinia virus and encoded recombinant antigens. Thus, the addition of an oil and water emulsion to MVA can increase the protective immune response. The invention encompasses administering a dose of an MVA in an oil and water emulsion to an animal, especially a human.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.