Patent · US Active

Biochemically stabilized HIV-1 Env trimer vaccine

US10653770B2 · kind B2 · utility

0Cited by

8References

19Claims

0Family size

Assignees

Inventors

Stephen C. Harrison · Cambridge, US
Bing Chen · Westwood, US
Dan H. Barouch · Newton, US
Joseph P. Nkolola · Watertown, US
Michael Scott Seaman · Dedham, US

Key dates

Filing date	Sep 23, 2019
Grant date	May 19, 2020
Priority date	—
Expiry date	Sep 23, 2039

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2740/16171
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.