Hydrogel-linked prodrugs releasing tagged drugs

US10653795B2 · kind B2 · utility

Assignee

• ASCENDIS PHARMA A/S · DK

Inventors

• Harald Rau · Würzburg, DE
• Nora Kaluza · Heidelberg, DE
• Ulrich Hersel · Heidelberg, DE
• Thomas Knappe · Heidelberg, DE
• Burkhardt Laufer · Birkenfeld, DE

Key dates

• Filing date: Apr 16, 2014
• Grant date: May 19, 2020
• Expiry date: Jul 27, 2034

Classification

• Technology area (CPC —): General

Abstract

The present invention relates to a process for the preparation of a hydrogel-linked prodrug releasing a tag moiety-biologically active moiety conjugate, to a hydrogel-linked prodrug releasing a tag moiety-bio logically active moiety conjugate obtainable by such process, to pharmaceutical compositions comprising said prodrug and their use as a medicament.