Urea compound and preparation method and application thereof
US10654815B2 · kind B2 · utility
13Cited by
0References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2017 |
| Grant date | May 19, 2020 |
| Priority date | — |
| Expiry date | Dec 27, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a urea compound and a preparation method and an application thereof. The structure of the present compound is represented by formula (I), the definition of each variable in the formula being as described in the description. The compound can block interaction between the PD-1/PD-L1 signalling pathways. The compound of the present invention can be used for treating or preventing diseases related to the signalling pathways, such as cancer, autoimmune disease, chronic infectious disease, and other diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.