Antibodies useful in passive influenza immunization

US10654915B2 · kind B2 · utility

Assignee

• Trellis Bioscience, Inc. · US

Inventors

• Lawrence M. Kauvar · San Francisco, US
• Stote Ellsworth · Palo Alto, US
• William Usinger · Lafayette, US
• Krista McCutcheon · Burlingame, US
• Minha Park · Brisbane, US

Key dates

• Filing date: Dec 5, 2012
• Grant date: May 19, 2020
• Expiry date: Dec 5, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Specific monoclonal antibodies and fragments including bispecific antibodies thereof that are crossreactive with multiple clades of influenza virus including both Group 1 and Group 2 representatives are disclosed. These antibodies are useful in controlling influenza epidemics and pandemics as well as in providing prophylactic or therapeutic protection against seasonal influenza.