Tagged multi-nucleotides useful for nucleic acid sequencing
US10655174B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | May 24, 2017 |
| Grant date | May 19, 2020 |
| Priority date | — |
| Expiry date | Nov 30, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/48721
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present disclosure relates to tagged multi-nucleotide compounds, which comprise a single tag moiety covalently linked to a plurality of nucleoside-5′-oligophosphate moieties. As disclosed herein, these tagged multi-nucleotide compounds have improved characteristics as polymerase substrates and can be used in a range of nucleic acid detection and sequencing methods, including nanopore sequencing-by-synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.