Dosing regimen for a selective S1P1 agonist
US10660880B2 · kind B2 · utility
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19References
4Claims
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Key dates
| Filing date | Jul 2, 2014 |
| Grant date | May 26, 2020 |
| Priority date | — |
| Expiry date | Jul 31, 2035 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a dosing regimen for a selective S1P1 receptor agonist, whereby the selective S1P1 receptor agonist is administered to a subject in such a way that during the initial treatment phase the selective S1P1 receptor agonist is administered at a dose which induces desensitization of the heart wherein said dose is below the target dose, and at a dosing frequency that sustains desensitization of the heart, until no further acute heart rate reduction occurs, followed by dose up-titration to the target dose of the selective S1P1 receptor agonist.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.