Composition, kit and method for inhibition of IL-21 mediated activation of human cells
US10662240B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Dec 15, 2015 |
| Grant date | May 26, 2020 |
| Priority date | — |
| Expiry date | Dec 15, 2035 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A synergistic composition, kit and method for inhibition and/or neutralization of IL-21 mediated activation of human cells including (i) a first agent being an antibody or antibody fragment thereof directed to a first epitope of IL-21, and (ii) a second agent being an antibody or antibody fragment thereof directed to a second epitope of IL-21 is disclosed. The inhibition and/or neutralization of IL-21 mediated activation of human cells is for use in the prophylaxis and/or treatment of disease of immune-related conditions including inflammatory disease, autoimmunity and lymphomas.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.