Patent · US Active

Optimized non-canonical zinc finger proteins

US10662434B2 · kind B2 · utility

0Cited by

12References

27Claims

0Family size

Assignees

DOW AGROSCIENCES LLC · US
Sangamo Therapeutics, Inc. · US

Inventors

Qihua C. Cai · Westfield, US
Vipula Shukla · Indianapolis, US
Joseph F. Petolino · Zionsville, US
Lisa W. Baker · Carmel, US
Robbi J. Garrison · Merrillville, US
Ryan C. Blue · Fishers, US
Jon C. Mitchell · West Lafayette, US
Nicole L. Arnold · Carmel, US
Sarah E. Worden · Fillmore, US
Jeffrey C. Miller · Pleasanton, US
Fyodor Urnov · Richmond, US

Key dates

Filing date	Nov 12, 2015
Grant date	May 26, 2020
Priority date	—
Expiry date	Oct 26, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2319/81
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.