Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers

US10668156B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Karl Kolter · Ludwigshafen am Rhein, DE
• Maximilian Angel · Mutterstadt, DE
• Matthias Karl · Ettlingen, DE
• Silke Gebert · Bad Kötzting, DE
• Michael Klemens MUELLER · Ludwigshafen, DE

Key dates

• Filing date: Jun 17, 2013
• Grant date: Jun 2, 2020
• Expiry date: May 18, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1635
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are solid dispersions of hydrophobic active ingredients and cationic copolymers of N,N-diethylaminoethyl methacrylate and methyl methacrylate in a weight ratio of the monomers of from 35:65 to 55:45. Also described are the preparation and use of such solid dispersions for pharmaceutical dosage forms.