Patent · US Active

Crystal form of fludarabine phosphate, preparation method therefor, and application thereof

US10669302B2 · kind B2 · utility

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10Claims

0Family size

Assignee

Zhejiang Hisun Pharmaceutical Co., Ltd. · CN

Inventors

Zhiqing Yang · Taizhou City, CN
Liang Zhang · Sichuan, CN
Xiangyang Zhang · Longbeilingcun, CN
Zhenjuan SHI · Taizhou City, CN
Di SU · Beijing, CN
Hongying Luo · Taizhou City, CN
Dejin Fu · Zhejiang, CN

Key dates

Filing date	Aug 26, 2016
Grant date	Jun 2, 2020
Priority date	—
Expiry date	Aug 26, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/13
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided are a new crystal form of fludarabine phosphate, a preparation method therefor, a pharmaceutical composition containing same, and an application thereof in preparing medicine. Crystal forms I and II of the fludarabine phosphate have excellent properties in terms of solubleness, dissolution rate, chemical stability, and processing adaptability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.