Selective detection of Haemophilus influenzae

US10669591B2 · kind B2 · utility

Assignee

• The Government of the United States of America as represented by the Secretary of the Deptartment of Health and Human Services · US

Inventors

• Jennifer Thomas · Hermosa Beach, US
• Xin Wang · Beijing, CN
• Cynthia Hatcher · Atlanta, US
• Raydel Anderson · Lawrenceville, US
• Mary Jordan Theodore · Atlanta, US
• Leonard W. Mayer · Decatur, US

Key dates

• Filing date: Jan 31, 2017
• Grant date: Jun 2, 2020
• Expiry date: Dec 5, 2037

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/16
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.