System and method for in vitro blood vessel modeling
US10670585B2 · kind B2 · utility
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6Claims
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Inventors
Key dates
| Filing date | Feb 23, 2017 |
| Grant date | Jun 2, 2020 |
| Priority date | — |
| Expiry date | Sep 22, 2038 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/0681
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides an in vitro blood vessel model for investigation of drug induced vascular injury and other vascular pathologies. The in vitro blood vessel model provides two channels separated by a porous membrane that is coated on one side by an endothelial cell layer and is coated on the other side by a smooth muscle cell layer, wherein said model is susceptible to the extravasation of red blood cells across said porous membrane due to drug induced vascular injury.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.