Method for producing pitavastatin calcium
US10676441B2 · kind B2 · utility
1Cited by
2References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 5, 2016 |
| Grant date | Jun 9, 2020 |
| Priority date | — |
| Expiry date | Aug 5, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B61/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Production of pitavastatin calcium safely on an industrial scale with a high yield and high selectivity at low cost. A method of producing pitavastatin calcium including step (i) for acetalizing a compound represented by the formula (1) to give a compound represented by the formula (3), step (ii) for reacting a compound represented by the formula (3) with an acid to give a compound represented by the formula (4), and step (iii) for hydrolyzing a compound represented by the formula (4) and reacting same with a calcium compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.