Antibodies useful in passive influenza immunization

US10676520B2 · kind B2 · utility

Assignee

• Trellis Bioscience, Inc. · US

Inventors

• Lawrence M. Kauvar · San Francisco, US
• Stote Ellsworth · Palo Alto, US
• William Usinger · Lafayette, US
• Krista McCutcheon · Burlingame, US
• Minha Park · Brisbane, US
• Bo Chen · Jinan, CN
• Ying-Ping Jiang · Scotch Plains, US

Key dates

• Filing date: Jun 17, 2011
• Grant date: Jun 9, 2020
• Expiry date: Jul 7, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Monoclonal antibodies and fragments thereof that are crossreactive with multiple clades of influenza virus including both Group 1 and Group 2 representatives are disclosed. These antibodies are useful in controlling influenza epidemics and pandemics as well as in providing prophylactic or therapeutic protection against seasonal influenza.