Microfluidic analysis system
US10676786B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2016 |
| Grant date | Jun 9, 2020 |
| Priority date | — |
| Expiry date | Oct 13, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2035/00514
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A microfluidic analysis system (1) performs polymerase chain reaction (PCR) analysis on a bio sample. In a centrifuge (6) the sample is separated into DNA and RNA constituents. The vortex is created by opposing flow of a silicon oil primary carrier fluid effecting circulation by viscous drag. The bio sample exits the centrifuge enveloped in the primary carrier fluid. This is pumped by a flow controller (7) to a thermal stage (9). The thermal stage (9) has a number of microfluidic devices (70) each having thermal zones (71, 72, 73) in which the bio sample is heated or cooled by heat conduction to/from a thermal carrier fluid and the primary carrier fluid. Thus, the carrier fluids envelope the sample, control its flowrate, and control its temperature without need for moving parts at the micro scale.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.