Assays and methods for detecting mycobacterial infections
US10677797B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 10, 2017 |
| Grant date | Jun 9, 2020 |
| Priority date | — |
| Expiry date | Mar 10, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/26
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein is an assay for detecting a rough-type mycobacterium and a smooth-type mycobacterium in a sample, wherein the mycobacterium is Mycobacterium tuberculosis or Mycobacterium bovis. The assay comprises a first molecule that selectively binds to the rough-type mycobacterium or binds to a molecule preferentially secreted by the rough-type mycobacterium and a second molecule that selectively binds to the smooth-type mycobacterium or binds to a molecule preferentially secreted by the smooth-type mycobacterium. The first molecule and the second molecule are independently detectable. Also provided herein are corresponding methods for detecting a rough-type mycobacterium and a smooth-type mycobacterium in a sample and assays and methods for detecting tuberculosis infection in a sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.