Color-changing eye drops for early screening alzheimer's disease and application thereof
US10677805B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2019 |
| Grant date | Jun 9, 2020 |
| Priority date | — |
| Expiry date | Jun 14, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/50
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to color-changing eye drops for early screening Alzheimer's disease and an application thereof. The color-changing eye drop for early screening Alzheimer's disease comprises 1 pg/ml to 10 ng/ml of Aβ42 aptamer-gold nanoparticles (AuNPs) and a pharmaceutically acceptable carrier or vehicle thereof, which can be used to mix with a tear sample of a test subject to analyze a color change of the color-changing eye drop for determining the concentration proportion of Aβ40:Aβ42 contained in the tear sample of the test subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.