Patent · US Active

Gastric retention active delivery systems

US10682307B2 · kind B2 · utility

1Cited by

2References

16Claims

0Family size

Assignee

Evonik Operations GmbH · DE

Inventors

Andrea Engel · Birmingham, US
Thomas Gottstein · Babenhausen, DE
Melanie Liefke · Ober-Ramstadt, DE

Key dates

Filing date	Oct 27, 2016
Grant date	Jun 16, 2020
Priority date	—
Expiry date	Oct 27, 2036

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K36/185
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a gastric retention active delivery system in the form of a coated capsule, which, in contrast to prior art delivery systems exhibiting relatively poor floating-properties, and thus requiring size expansion capability in order to securely delay passage through the pylorus, reliably stay afloat for several hours. This is achieved by combining pore forming components and flexible polymer components in the coating in suitable proportions. The present invention, further, relates to the use of gastric retention active delivery systems of the invention for the delivery of one or more water soluble active components A to a mammal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.