Mutant Bordetella strains and methods of use
US10682377B2 · kind B2 · utility
4Cited by
3References
11Claims
0Family size
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Key dates
| Filing date | Mar 29, 2017 |
| Grant date | Jun 16, 2020 |
| Priority date | — |
| Expiry date | Jul 15, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of reducing or preventing the development of airway inflammation in a subject includes the step of infecting the respiratory tract of a subject an amount of a composition including a pharmaceutically acceptable carrier and live attenuated pertactin-deficient Bordetella bacteria sufficient to colonize the respiratory tract of the subject. The step of infecting the subject with the live attenuated pertactin-deficient Bordetella bacteria results in reduction or prevention of the development of airway inflammation in the subject.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.