Cannabidiol-3-sulfonic acid, preparation method and application thereof, and cannabidiol derivative
US10683265B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 7, 2019 |
| Grant date | Jun 16, 2020 |
| Priority date | — |
| Expiry date | Oct 7, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention relates to a cannabidiol-3-sulfonic acid, a preparation method and application thereof, and a cannabidiol derivative. The present invention introduces a sulfonic acid group in a molecular structure of cannabidiol, and the sulfonic acid group as a polar group can increase the polarity of cannabidiol, thereby improving the water solubility thereof. The cannabidiol-3-sulfonic acid can be subjected to a salt forming reaction with an inorganic base or an organic base, so that the water solubility of the cannabidiol is further improved, and the druggability of a drug based on a parent nucleus and physiological activity of the CBD structure can be enhanced. The newly introduced sulfonic acid group in the cannabidiol-3-sulfonic acid provided by the present invention can be used as a new action site to react with a specific group, and the research and application range of the cannabidiol-3-sulfonic acid is further broadened.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.