Patent · US Active

Compounds, linker-drugs and ligand-drug conjugates

US10683327B2 · kind B2 · utility

0Cited by
14References
6Claims
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Assignee

Inventors

Key dates

Filing dateDec 11, 2018
Grant dateJun 16, 2020
Priority date—
Expiry dateDec 11, 2038

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/0207
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), R1, R2 and R3 are each, independently, hydrogen, amino, nitro, halogen, hydroxyl, C1-C6 alkoxy, carboxylic acid, C1-C6 alkoxycarbonyl, C1-C6 amino, C1-C6 aminocarbonyl, C1-C6 alkyl, branched C1-C6 alkyl, C1-C6 cycloalkyl, C1-C6 heterocyclic, aryl or heteroaryl, provided at least one of R1 and R3 is an amino group. A linker-drug and a ligand-drug conjugate including the compound are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.