Patent · US Active

Tubular nanostructure targeted to cell membrane

US10683365B2 · kind B2 · utility

0Cited by

31References

43Claims

0Family size

Assignee

Deep Science, LLC · US

Inventors

Mahalaxmi Gita Bangera · Renton, US
Ed Harlow · Boston, US
Roderick A. Hyde · Redmond, US
Muriel Y. Ishikawa · Livermore, US
Edward K.Y. Jung · Bellevue, US
Eric C. Leuthardt · Chesterfield, US
Nathan P. Myhrvold · Bellevue, US
Dennis J. Rivet · Chesapeake, US
Elizabeth A. Sweeney · Seattle, US
Clarence T. Tegreene · Bellevue, US
Lowell L. Wood, JR. · Bellevue, US
Victoria Y.H. Wood · Livermore, US

Key dates

Filing date	Mar 8, 2017
Grant date	Jun 16, 2020
Priority date	—
Expiry date	Mar 19, 2037

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S977/915
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Devices, compositions, and methods are described which provide a tubular nanostructure or a composite tubular nanostructure targeted to a lipid bilayer membrane. The tubular nanostructure includes a hydrophobic surface region flanked by two hydrophilic surface regions. The tubular nanostructure is configured to interact with a lipid bilayer membrane and form a pore in the lipid bilayer membrane. The tubular nanostructure may be targeted by including at least one ligand configured to bind to one or more cognates on the lipid bilayer membrane of a target cell.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.