Polymers, hydrogels, and uses thereof

US10683379B2 · kind B2 · utility

Assignee

• Massachusetts Institute of Technology · US

Inventors

• Daniel Griffith Anderson · Framingham, US
• Eric A. Appel · Palo Alto, US
• Yizhou Dong · Lexington, US
• Robert S. Langer · Newton, US
• Benjamin C. Tang · Cambridge, US
• Omid Veiseh · Bellaire, US
• Weiheng Wang · Bedford, US
• Matthew J. Webber · South Bend, US
• Kun Xue · Cambridge, US

Key dates

• Filing date: Mar 23, 2016
• Grant date: Jun 16, 2020
• Expiry date: Mar 23, 2036

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F2810/50
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described herein are polymers, polymeric gels, or a composition thereof, for drug delivery. The polymers, which include boronic-acid containing moieties (e.g., and polyol-containing moieties (e.g., are prepared by free-radical polymerization and can self-assemble into polymeric gels such as hydrogels. Also provided are methods or preparing the polymers, kits involving the polymers and/or polymeric gels or a composition thereof, for use as materials or delivery applications of an agent to a subject.