Patent · US Active

HNF4G-RSPO2 fusion gene and use thereof in treatment of cancer

US10683550B2 · kind B2 · utility

0Cited by

0References

7Claims

0Family size

Assignee

CROWN BIOSCIENCE, INC. (TAICANG) · CN

Inventors

Jie Cai · Oceanside, US
Henry Qixiang Li · Russell, CA

Key dates

Filing date	Apr 3, 2015
Grant date	Jun 16, 2020
Priority date	—
Expiry date	Jun 29, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present disclosure provides methods of detecting a fusion gene of HNF4G and RSPO2 in a nucleic acid-containing sample, and a primer set, a probe set and a kit for detecting the fusion gene are also provided. Animal models for a human disease positive for the fusion gene are also provided herein. In addition, the present disclosure relates to the methods for assessing and identifying an agent effective on the fusion gene of HNF4G and RSPO2 or a human disease positive for a fusion gene of HNF4G and RSPO2 and thereby treating said disease are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.