Sample collection and bioluminescent analysis system

US10684232B2 · kind B2 · utility

Assignee

• BIOCONTROL SYSTEMS, INC. · US

Inventors

• Marc Warren Gordon · Carnation, US
• Jon Keith Perrin · Redmond, US
• Alexander Michael Diener · Federal Way, US
• David Oscar Iverson · Seattle, US
• Kyle Stuart Johnson · Sammamish, US
• Garet Glenn Nenninger · Seattle, US
• John R. Murkowski · Seattle, US
• Kristin Marie Will · Seattle, US
• Chad Austin Brinckerhoff · Issaquah, US
• Phillip T. Feldsine · Mercer Island, US
• Tim Allen Kelly · Bellevue, US

Key dates

• Filing date: Aug 4, 2016
• Grant date: Jun 16, 2020
• Expiry date: Oct 29, 2037

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2201/065
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods and apparatus for evaluating the quality of an environment or process by measuring light emitted from a bioluminescent sample containing ATP, ADP, or alkaline phosphatase. The apparatus comprises a sample collection and analysis system used to collect a sample, mix reagents, react the sample, and collect it in a measurement chamber. The system includes an instrument having a photon detection assembly for use with the sample testing device and one or more probe assemblies that optically cooperate with the instrument. The instrument includes a dark chamber with a reflective interior surface which may be concave or preferably spherical, and a photon detection sensor such as a multi-pixel photon counter sensor. A substantially transparent portion of the probe assembly, and liquid contained therein, focus bioluminescence toward the photon detection sensor.