Dual flip angle multi-echo ultra-short echo time (DUFA-MUTE) magnetic resonance imaging (MRI) systems and methods
US10684339B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 16, 2018 |
| Grant date | Jun 16, 2020 |
| Priority date | — |
| Expiry date | Oct 7, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/10088
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Systems and methods for producing pseudo-CT images using a dual flip angle multi-echo ultra-short echo time (DUFA-MUTE) MRI method are disclosed. The DUFA-MUTE MRI imaging method includes obtaining MR signals according to a DUFA-MUTE MRI sequence that includes first and second multiple ultrashort echo time (MUTE) sequence characterized by first and second flip angles FA1/FA2, and in which both MUTE sequences obtain MR signals at first and second echo times TE1/TE2. HU values are assigned to each imaged voxel based on each voxel's R1 value calculated from the MR signals, as well as each voxel's assigned tissue type. The imaged voxels and assigned HU values are combined to produce a pseudo-CT image. Pseudo-CT images optionally form the basis for attenuation maps suitable for use in combined PET/MRI systems and/or electron density maps suitable for use in radiation therapy systems.
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