Methods and compositions for treating aging-associated conditions

US10688130B2 · kind B2 · utility

Assignees

• The Board of Trustees of the Leland Stanford Junior University · US
• U.S. Government as represented by the Department of Veterans Affairs · US

Inventors

• Anton Wyss-Coray · Palo Alto, US
• Saul A. Villeda · Lancaster, US
• Joseph M. Castellano · Tuckahoe, US
• Jinte Middeldorp · Utrecht, NL
• Martin S. Angst · Palo Alto, US
• Jian Luo · Palo Alto, US

Key dates

• Filing date: Dec 5, 2014
• Grant date: Jun 23, 2020
• Expiry date: Jun 17, 2035

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P27/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.