PH-sensitive linkers for delivering a therapeutic agent
US10688193B2 · kind B2 · utility
0Cited by
0References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 2016 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Jul 21, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2300/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a pH-sensitive linker that can simultaneously bind metallic nanoparticles and one or more agents with various molecular size. The linker of the invention can deliver the agents into cells involved in disease processes or close to cells so that the agents can selectively target and effect on the cells. The target delivery provided by the linker of the invention can be used for example for disease sensing, imaging, drug delivery, and therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.