Theranostic bubble preparation (TB), and method for using same
US10688199B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2016 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Jul 14, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a theranostic bubble preparation which makes it possible to diagnose and treat a tissue of interest by the irradiation with ultrasound such as diagnostic ultrasound and low-intensity therapeutic ultrasound. The theranostic bubble preparation comprises: a coating film comprising a lipid; and a gas enclosed in an inner cavity formed in the coating film. The coating film comprises an anionic lipid made from distearoylphosphatidylcholine (DSPC), distearoylphosphatidylglycerol (DSPG) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000). The gas and the mixed gas comprises perfluoropropane or perfluorobutane.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.