Crystalline forms of 1-(4-{[6-amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone

US10689363B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Axel Becker · Altrip, DE
• Marco Poma · Grosseto, IT
• Edoardo Burini · Guidonia, IT
• Christoph Saal · Otzberg, DE
• Vedad Theuerkorn · Pfungstadt, DE

Key dates

• Filing date: Sep 23, 2019
• Grant date: Jun 23, 2020
• Expiry date: Sep 23, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07B2200/13
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A solid form of 1-(4-{[6-Amino-5-(4-phenoxy-phenyl)-pyrimidin-4-ylamino]-methyl}-piperidin-1-yl)-propenone, or pharmaceutically acceptable salts thereof, are useful as BTK inhibitors.