Process for the preparation of cyclic depsipeptides

US10689419B2 · kind B2 · utility

Assignee

• OnKure, Inc. · US

Inventors

• Anthony D. Piscopio · Longmont, US
• Xiaoyong Fu · Edison, US
• Feng Shi · Beijing, CN
• Huayan Liu · Shanghai, CN
• Zhifeng Li · Arlington, US

Key dates

• Filing date: Sep 11, 2018
• Grant date: Jun 23, 2020
• Expiry date: Sep 11, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K11/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Processes for preparing compounds of Formula (1) and Formula (2) are described, wherein X, Y, Z, R1-R7, L and n are defined herein. Intermediates useful in the preparation of the compounds of Formula (1) and Formula (2) are also described.