Recombinant monovalent antibodies
US10689444B2 · kind B2 · utility
0Cited by
4References
11Claims
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Key dates
| Filing date | Jan 26, 2017 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Jan 26, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to recombinant monovalent antibodies which are heterodimers of a first protein chain comprising the variable domain of the heavy chain of an antibody of interest and the CH2 and CH3 domains of an IgG immunoglobulin and a second protein chain comprising the variable domain of the light chain of said immunoglobulin of interest and the CH2 and CH3 domains of said IgG immunoglobulin. These antibodies can be used in particular as therapeutic agents in all cases where monovalent binding to a ligand such a cellular receptor is required.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.