Patent · US Active

Multimeric death domain-containing receptor-5 (DR5) antibodies and uses thereof

US10689449B2 · kind B2 · utility

11Cited by

31References

30Claims

0Family size

Assignee

IGM Biosciences, Inc. · US

Inventors

Beatrice Tien-Yi Wang · Mountain View, US
Max Allen Schwarzer · Los Altos, US
Bruce Keyt · Pacifica, US
Ramesh Baliga · Redwood City, US

Key dates

Filing date	Jan 20, 2016
Grant date	Jun 23, 2020
Priority date	—
Expiry date	Jan 20, 2036

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/75
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.