Patent · US Active

BCMA binding molecules and methods of use thereof

US10689450B2 · kind B2 · utility

0Cited by
21References
71Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 31, 2017
Grant dateJun 23, 2020
Priority date
Expiry dateMar 31, 2037

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/33
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides antibodies, antigen binding fragments thereof, chimeric antigen receptors (CARs), and engineered T cell receptors, polynucleotides encoding the same, and in vitro cells comprising the same. The polynucleotides, polypeptides, and in vitro cells described herein can be used in an engineered CAR T cell therapy for the treatment of a patient suffering from a cancer. In one embodiment, the polynucleotides, polypeptides, and in vitro cells described herein can be used for the treatment of multiple myeloma.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.