Systems, methods, and devices for detecting leaks in a chromatography system
US10690563B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jan 16, 2018 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | Mar 17, 2038 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/027
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Systems, methods, and devices for detecting leaks in chromatography systems are disclosed. A coating is disposed to conform to at least one component of a chromatography system, such as a fitting or a section of tubing. The coating is made of or contains a responsive material that can undergo a detectable change when exposed to a chromatographic fluid or mobile phase. The change of the responsive material can indicate the presence of the fluid or mobile phase, a change in at least one physical property of the coating to prevent passage of the fluid or mobile phase, or a combination thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.