Purification of glucagon-like peptide 1 analogs
US10690635B2 · kind B2 · utility
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Key dates
| Filing date | Mar 21, 2017 |
| Grant date | Jun 23, 2020 |
| Priority date | — |
| Expiry date | May 20, 2037 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/065
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention refers to a method of purifying a glucagon-like peptide 1 analogs, the method comprising a two dimensional reversed phase high performance liquid chromatography protocol, wherein the first step is carried out at a pH value between 7.0 to 7.8 using a mobile phase comprising a phosphate buffer and acetonitrile, and the second step is carried out at a pH value below 3.0 using a mobile phase comprising trifluoroacetic acid and acetonitrile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.