Liquid chromatography system for sample loading with a trap column

US10690639B2 · kind B2 · utility

Assignee

• Dionex Softron GmbH · DE

Inventors

• Thomas Wachinger · Hohenzell, DE
• Christoph Hollnagel · Gauting, DE

Key dates

• Filing date: Nov 10, 2017
• Grant date: Jun 23, 2020
• Expiry date: Jul 24, 2038

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2030/385
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A liquid chromatography system includes a separation column, a trap column, and a first switching valve. The first switching valve is adapted to assume a first switching position for bringing a sample into the trap column in a first flow direction. The switching valve is also adapted to assume a second switching position for fluidly connecting the trap column with the separation column and providing a flow from the trap column to the separation column in a second flow direction. The second flow direction is opposite to the first flow direction. The first switching valve is adapted to assume a third switching position for fluidly connecting the trap column, with the separation column and providing a flow from the trap column to the separation column in the first flow direction.