Magnetic apparatus and methods of use
US10695036B2 · kind B2 · utility
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2References
20Claims
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Key dates
| Filing date | Aug 15, 2016 |
| Grant date | Jun 30, 2020 |
| Priority date | — |
| Expiry date | Jul 23, 2037 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T29/49
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein is a magnetic apparatus for collecting superparamagnetic particles from a subject. The superparamagnetic particles are previously injected into the subject and have ligands bound thereto that are specific for one or more non-cell biomarkers. In one embodiment, the superparamagnetic particles are injected into and retrieved from a cavity such as a joint cavity. These compositions and methods allow for the sequestration and removal of inflammatory mediators, as both a diagnostic of the local immune response and a therapeutic that can reduce inflammation in the local disease environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.