Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors

US10695334B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Matthias Eckhardt · Hannover, DE
• Andreas Gollner · Wien, AT
• Elke Langkopf · Biberach an der Riß, DE
• Holger Wagner · Mettenberg, DE
• Dieter Wiedenmayer · Biberach an der Riß, DE

Key dates

• Filing date: Aug 14, 2019
• Grant date: Jun 30, 2020
• Expiry date: Aug 14, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Heteroaromatic carboxamides of formula (I), wherein Y, R, and X are as defined herein, and pharmaceutically acceptable salts thereof. The compounds of formula (I) can be used in methods for the treatment of diseases which can be influenced by inhibition of plasma kallikrein.