Interventional drug delivery system and associated methods

US10695562B2 · kind B2 · utility

Assignee

• The University of North Carolina at Chapel Hill · US

Inventors

• Joseph M. DeSimone · Monte Sereno, US
• Mary Napier · Chapel Hill, US
• Jonathan Pillai · Pune, IN
• James Byrne · Chapel Hill, US
• Lukas Miller Roush · Pleasanton, US
• Jen Jen Yeh · Chapel Hill, US
• Matt Parrott · Carrboro, US

Key dates

• Filing date: Jun 24, 2015
• Grant date: Jun 30, 2020
• Expiry date: Apr 30, 2038

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N1/36002
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A delivery system for local drug delivery to a target site of internal body tissue is provided. The delivery system comprises a source electrode adapted to be positioned proximate to a target site of internal body tissue. A counter electrode is in electrical communication with the source electrode, and is configured to cooperate with the source electrode to form a localized electric field proximate to the target site. A reservoir is configured to be disposed such that the reservoir is capable of interacting with the localized electric field. The reservoir is configured to carry a cargo capable of being delivered to the target site when exposed to the localized electric field. Associated methods are also provided.