Mass spectrometer with a laser desorption ion source, and laser system with a long service life
US10699891B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Dec 22, 2015 |
| Grant date | Jun 30, 2020 |
| Priority date | — |
| Expiry date | Feb 19, 2036 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/403
- WIPO fieldElectrical machinery, apparatus, energy
- WIPO sectorElectrical engineering
Abstract
The invention relates to a mass spectrometer with laser-desorption ion source, particularly for MALDI. A laser system with optical laser spot control is proposed in which the laser spot shift brought about by means of a temporally variable angular deflection at a mirror system is performed on the laser beam before or during the energy multiplication. The laser beam, which is deflected through a small angle by the mirror system, is converted by a suitable flat-field optical system into a parallel-shifted laser beam, which then passes through a multiplier crystal. After exiting the multiplier crystal system, the parallel-shifted beam is converted back into a slightly angled beam by a flat-field optical system, this latter beam then bringing about the spot shift on the sample. The multiplier crystal is conserved by the continuously temporally changed parallel shift of the laser beam in the multiplier crystal, thus prolonging its service life.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.