Compositions containing protein loaded exosome and methods for preparing and delivering the same
US10702581B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Nov 3, 2017 |
| Grant date | Jul 7, 2020 |
| Priority date | — |
| Expiry date | Nov 3, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a method for the mass-production of exosome comprising a cargo protein, a vector for preparing the exosome, exosome including a cargo protein prepared by the method, and a method for loading the cargo protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a cargo protein provided by the present invention, the exosome loaded with a cargo protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.