TNF receptor signaling modulator assay
US10705094B2 · kind B2 · utility
9Cited by
6References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 22, 2015 |
| Grant date | Jul 7, 2020 |
| Priority date | — |
| Expiry date | Oct 22, 2035 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Accordingly, these compounds can be used as modulators of TNF. A new assay for identifying compounds with this mechanism of action is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.