Accelerated aging for polymeric scaffolds
US10709589B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 9, 2017 |
| Grant date | Jul 14, 2020 |
| Priority date | — |
| Expiry date | Jan 10, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2210/0004
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of accelerated aging of bioresorbable polymer scaffolds including exposing the scaffold to water is disclosed. The scaffold is exposed to water at a controlled temperature for a selected aging time. The functional outputs, such as radial strength, expandability, and % recoil obtained from aged scaffolds predict those of real-time aging of the scaffold. The accelerated aging factor, which is the required shelf life divided by the aging time, is significantly higher for poly(L-lactide) scaffolds tested than thermal aging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.